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Recombinant Varicella Zoster Virus gE (VZV gE) antibody (Biotin)

The Human Monoclonal anti- antibody has been validated for ELISA. It is suitable to detect in samples from Varicella Zoster Virus (VZV).
Catalog No. ABIN7488728

Quick Overview for Recombinant Varicella Zoster Virus gE (VZV gE) antibody (Biotin) (ABIN7488728)

Target

Varicella Zoster Virus gE (VZV gE)

Antibody Type

Recombinant Antibody

Reactivity

Varicella Zoster Virus (VZV)

Host

  • 1
  • 1
Human

Clonality

  • 2
Monoclonal

Conjugate

  • 2
Biotin

Application

  • 2
  • 1
  • 1
ELISA

Clone

4G2
  • Purpose

    Biotinylated Monoclonal Anti-Glycoprotein E (VZV) Antibody, Human IgG1 (4G2)

    Isotype

    IgG1
  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Storage

    -20 °C
  • Target

    Varicella Zoster Virus gE (VZV gE)

    Alternative Name

    VZV gE

    Target Type

    Viral Protein

    Background

    Varicella-zoster virus (VZV) is a neurotropic virus belonging to the Herpesviridae family. Primary VZV infection causes chickenpox and is followed by a life-long latent infection established mainly in the cranial and dorsal root ganglia. Reactivation of the virus is often associated with shingles (herpes zoster). Glycoprotein E (gE) is one of the known glycoproteins (gB, gC, gE, gH, gI, gK, gI) of VZV that is most abundantly expressed on the surface of virus and infected cells, playing an important role in viral replication and cell-to-cell spread. The strongly immunogenic gE can provide strong IgG signal in body fluid, which makes it ideal to be developed as an antigen for analysis of IgG antibodies. gE also demonstrates high potency as a vaccine immunogen and is formulated as the single viral envelope protein that constitutes the GSK VZV recombinant subunit vaccine Shingrix®.The antibody can reacte with gE specially.
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